Cell therapy developers should start thinking about automation early – future-proofing manufacturing strategies, reducing long-term regulatory hurdles, and de-risking scale-up. However, you shouldn’t feel under any pressure to implement early.  Do so when the timing is right for you.

Constellation provides complete flexibility – you can adopt automation at any time and at the pace that suits your development timeline. Unlike fixed, inflexible systems that lock you into a specific process, Constellation allows you to scale seamlessly from clinical to commercial manufacturing without process changes. This means you can continue refining your process manually while keeping automation in mind, knowing that Constellation can integrate when the time is right.

With Constellation, you retain full control over when and how you automate, ensuring your technology and processes evolve on your terms.

Constellation is designed for regulatory compliance from the ground up. It maintains GMP-aligned processing and provides comprehensive electronic batch records (EBR) for full traceability. By mirroring manual operations within a controlled, automated system, Constellation standardises processes, minimising deviations and risk of errors, and can be introduced without requiring significant process revalidation—accelerating the path to commercialisation without regulatory roadblocks.

Constellation is not a fixed, rigid system.  It is a flexible automation platform which combines your existing, proven technologies and processes and automates them within one unified hardware and digital layer.

Our mobile robots transport product, consumables and reagents between workstations housing proven third-party technologies, operating those unit operations and automating all critical GMP manufacturing steps. A unified digital layer ensures seamless integration, real-time monitoring, and full traceability.

By using existing, regulatory-approved technologies, Constellation enables rapid scale-up only when needed – lowering regulatory risk, reducing labour, maximising facility efficiency, and de-risking the journey to commercial-scale manufacturing. It is a truly flexible and adaptable option to scale to suit you and your requirements.

Not necessarily. You can deploy our solution within your existing facility or opt to build a new one.  It entirely depends on your objectives, stage of development, and commercial ambitions.

Constellation is designed to provide flexibility. It can integrate into established environments or form the foundation of a purpose-built facility optimised for scale. Many organisations choose to begin within their current infrastructure to develop and refine their processes without overcommitting capital too early. This allows teams to focus on achieving process robustness and clinical success before scaling into a larger, more permanent manufacturing setup.

When you’re ready, Constellation enables a seamless transition into a full-scale, modular factory model, without needing to redesign your process. This approach minimises risk, maximises efficiency, and ensures you only invest in new infrastructure when you’re confident in your manufacturing process and market trajectory. In short, it’s about what’s right for your journey: start where you are, scale when you’re ready.

Constellation is designed to enhance, not replace, operator expertise. While manual processes introduce variability and reliance on skilled technicians, Constellation standardises key process steps while allowing operators to focus on process oversight, decision-making, and innovation. Real-time monitoring and intuitive operator interfaces ensure that teams maintain full visibility and control over the manufacturing process, allowing manual intervention alongside automation if necessary, without interrupting the workflow.

Constellation is specifically designed to de-risk cell therapy manufacturing by eliminating the most common failure points associated with manual processing. By integrating precision robotics, closed-system automation, and sterile welding, Constellation reduces contamination risk, process variability, and reliance on skilled labour – three of the biggest challenges in cell therapy production.

Unlike traditional manual workflows, where human intervention increases the likelihood of errors and inconsistencies, Constellation provides standardised, repeatable execution at every stage. Furthermore, real-time monitoring and digital batch recording within one unified digital layer provides complete traceability, allowing for proactive issue detection and seamless regulatory compliance.

Crucially, Constellation has been engineered with practical flexibility in mind. If a unit requires maintenance or unexpected attention, human operators can safely intervene in that specific area without needing to shut down the entire process. This modular design not only ensures operational continuity, but also adds a vital layer of resilience and confidence in manufacturing uptime.

Constellation delivers a measurable return on investment, often from the earliest stages of deployment, by reducing reliance on highly skilled labour, increasing production throughput, and minimising batch variability. It’s a capital-efficient solution that aligns with both early-stage clinical needs and commercial scalability.

Unlike traditional manufacturing setups that require large manual teams, extensive training programmes, and expansive cleanroom footprints, Constellation enables a leaner, more efficient, and space-optimised operational model. Over time, automation drives down cost per dose, accelerates time to market, and improves facility utilisation, ensuring long-term cost-effectiveness without compromising process control or compliance.